Rejuran · Polynucleotide · Seomyeon, Busan

Healing from within, from salmon DNA.

Rejuran uses polynucleotides (PN) from salmon DNA to repair skin from the inside — improving texture, elasticity, pore size and that overall "skin quality" glow. Not a filler, a healer. A 3–4 session cycle from ₩150,000 at JRYN Seomyeon, for skin that simply looks better.

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Rejuran treatment at JRYN Dermatology Seomyeon Busan

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20 min

Treatment

2–3 wks

Visible Results

6–9 mo

Duration

None

Downtime

3–4

Sessions

₩ 150k+

From

What Is Rejuran?

The original skin-quality healer.

Rejuran uses polynucleotides (PN) extracted and purified from salmon DNA — biocompatible molecules that trigger your skin's own repair processes. Rather than filling or freezing, it improves skin from within: texture, elasticity, fine lines, pore size and resilience.

The result is harder to point at but easy to see — skin that looks healthier, smoother and more "lit from within". Best as a 3–4 session cycle two weeks apart, lasting 6–9 months. At JRYN Seomyeon, Rejuran runs from ₩150,000 (Standard PN) to ₩350,000 (Eye), per session.

How It Works

The science, without the hype.

Understanding the mechanism helps you set realistic expectations — and see why technique matters more than brand here.

Salmon-derived PN

Purified polynucleotides are injected into the dermis, where they're recognised as natural repair signals.

Skin repair switches on

PN stimulates fibroblasts and tissue repair, improving collagen, elasticity and hydration from within.

Quality, not volume

You don't get bigger or frozen — your skin simply works better: smoother, denser, more resilient.

A short cycle

3–4 sessions two weeks apart build the effect; results hold 6–9 months with periodic top-ups.

Where We Inject

Where we inject, and why.

Each area has its own concern and dose. Dr. Lee maps yours in person — these are starting points, not fixed packages.

Full Face

All-Over

Overall texture, dullness, aging.

Dose 2ml / session

Results 2–3 wks

Cheeks

Pores

Pore size and mild laxity.

Dose 1ml / side

Results 3–4 wks

Forehead

Lines

Fine lines and dry texture.

Dose 0.5–1ml

Results 2–3 wks

Neck & Décolletage

Crepe

Crepey skin, sun lines.

Dose 1–2ml

Results 4–6 wks

Doses are typical starting ranges for foreign patients, personalised at your free consultation. Best results come from a 3–4 session cycle.

Rejuran Pricing

Your options, side by side.

All our skin boosters are clinically safe in licensed hands. They differ in mechanism, longevity and price — we'll match the right one to your skin, never the priciest.

Brand	Price	Best for	Duration
Rejuran Standard PN	₩150,000	First-timers, overall skin quality	6–9 mo
Rejuran S (Scar)	₩250,000	Acne scars, texture irregularity	6–9 mo
Rejuran HB+ (Hydro)	₩300,000	Deep hydration with HA blend	6–9 mo
Rejuran I (Eye)	₩350,000	Under-eye dark circles, fine lines	6–9 mo

Guide prices for foreign patients, per session. A 3–4 session cycle is recommended for the full effect. Korean medical advertising rules limit fixed online pricing; message us for an exact quote before you travel.

Honest Candidacy

Who it suits — and who should wait.

A good fit if you…

Want better "skin quality" — texture, pores, elasticity
Prefer healing and repair over filling or freezing
Have dull, tired or early-aging skin
Can commit to a short 3–4 session cycle

Better to wait if you…

Want instant volume or wrinkle freezing — that's filler or botox
Are pregnant or breastfeeding
Have a known fish/salmon allergy — tell us first
Can't return for the full cycle of sessions

After your treatment

Small injection bumps for 24 hours are normal
Mild redness or tenderness settles quickly
Avoid makeup for the rest of the day
Avoid saunas and intense exercise for 24 hours

Possible side effects

Tiny bumps flatten within a day or so
Results build over 2–3 weeks per session
Stay hydrated and gentle on skincare for 48 hours
We review you on WhatsApp after you fly home, in your language

Our Medical Team

Three doctors, one standard of care.

Your Rejuran course is injected in person by one of our doctors — founded and guided by Dr. Jeong Heon Lee since 2007.

Dr. Jeong Heon Lee, board-certified dermatologist at JRYN Seomyeon Busan

Your Injector

Rejuran is about skin that works better.

Patients struggle to describe what Rejuran does because it doesn't change your shape — it changes your skin's quality. Texture, glow, resilience. Done as a proper cycle, it's one of the most natural rejuvenations I offer, and it's why so many keep coming back.

Board-certified dermatologist · MD, Inje University College of Medicine
Founder, JRYN Dermatology (2007) · polynucleotide-therapy specialist
Verified-dose products only · Korean MFDS & FDA-approved brands
A calm, unhurried consultation — your dose is planned, not guessed

Chief Director · Seomyeon Main Branch

Dr. Yoon Jung-wook

Full Member, Korean Society of Aesthetic Plastic Surgery
Full Member, Korean Society for Aesthetic Plastic Surgery & Laser Medicine
Full Member, Korean Society of Obesity & Body Contouring

Former Neurosurgery Resident (3rd Year), Dong-A University Hospital
Former Intern, Dong-A University Hospital
Former Chief Director, Forever Plastic Surgery & Dermatology (Changwon)
Former Director, Forever Plastic Surgery & Dermatology (Haeundae)
Former Chief Director, Lovely Plastic Surgery & Dermatology (Changwon)
Former Director, Insta Plastic Surgery & Dermatology (Gimhae)
Former Director, Dr. Yoon Beauty Center (Vietnam)

Vice Chief Director · Seomyeon Main Branch

Dr. Jin Tae-wan

Former Director of Dermatology, MediWoman Women's Clinic
Former Director of Dermatology, Hangdo Quantum Clinic
Former Chief Director, AGE Clinic (formerly Paresa Clinic)

Former Chief Director, One Clinic (Guro)
Former Director, One Clinic (Gangnam)
Former Chief Director, SKY Plastic Surgery (Jongno)
Former Visiting Physician, Guangfu Aesthetic Plastic Surgery Hospital (Dalian, China)
Former Associate Director, Tokeshi Plastic Surgery
Former Associate Director, Midam Dermatology Clinic
Former Associate Director, Noble Line Plastic Surgery
Former Associate Director, Jeniva Plastic Surgery
Former Military Flight Surgeon, ROK Army Aviation Operations Command
Former Intern & Resident, Kangdong Sacred Heart Hospital

Rejuran FAQ

Good to know.

At JRYN Seomyeon, Rejuran Standard is ₩150,000, Rejuran S (scar) ₩250,000, HB+ (hydro) ₩300,000, and Rejuran I (eye) ₩350,000, per session. A 3–4 session cycle is recommended. We confirm your exact quote free in consultation or over WhatsApp.

It improves "skin quality" — texture, elasticity, pore size, fine lines and resilience — by using salmon-derived polynucleotides to switch on your skin's own repair. It doesn't add volume or freeze movement; it makes skin work better.

Standard PN for overall quality, Rejuran S for acne scars and texture, HB+ for dryness (with HA), and Rejuran I for the under-eye. Dr. Lee recommends the right one — or a combination — in consultation.

Each session shows over 2–3 weeks, building across the cycle. A full 3–4 session course lasts 6–9 months, maintained with periodic top-ups.

Numbing cream is applied, and most tolerate it well. Tiny injection bumps and mild redness settle within about a day. You can fly the same day.

Yes — English, Japanese and Chinese. We're a 5-minute walk from Seomyeon Station, 45 minutes from Gimhae Airport, and review your progress on WhatsApp after you fly home.

More Skin Boosters at JRYN

Explore other areas.

Juvelook & Collaum

Korean PDLLA collagen builder.

from ₩350,000

Rejuran Eye

Under-eye repair, no filler.

from ₩250,000

Rejuran Healer

Concentrated PN for deep repair.